Abstract:
Medicinal plants remain a reliable source of active principles renowned for their therapeutic
properties. In this context, our study focuses on the phytochemical and biological analysis of
two Algerian species: Lysimachia monelli and Genista microcephala.
The quantification of total polyphenols and flavonoids in Lysimachia monelli extracts was
performed using colorimetric methods. This analysis revealed significant contents of
polyphenols and flavonoids in butanolic and ethyl acetate extracts, respectively.
We also evaluated the antioxidant activity of organic extracts of L. monelli using four
different methods: DPPH, ABTS, FRAP, and Phenanthroline. These tests showed promising
results compared to standard antioxidants.
The antibacterial activity of the essential oil and extracts was evaluated against four
pathogenic bacteria. The results revealed a modest effectiveness against the studied bacterial
strains.
The antifungal activity was tested on a fungal strain: Fusarium oxysporum using the solid
medium diffusion method, showing remarkable inhibition zones.
Additionally, the chemical composition of the essential oil was analyzed by GC-MS,
identifying 77.32% monoterpenes, 0.89% sesquiterpenes, 3.59% alkanes, and 12.59% other
compounds. This oil is predominantly composed of limonene (57.24%), pulegone (12.05%),
β-pinene (4.2%), and n-hexadecanoic acid (3.11%).
Therefore, these plants could be further explored for therapeutic and pharmaceutical
applications due to their antioxidant and antifungal properties.
