Abstract:
This thesis represents a pioneering and unique advancement in Algeria, being the
first research on the preparation of an innovative cream for vasodilation and the
visual detection of blood vessels, aimed at facilitating blood sampling and injection
using natural plant extracts. The study focuses on two types of natural plants, one
local (Algerian) and the other from East Asia. The extracts obtained were initially
subjected to tests to evaluate their antioxidant activities (DPPH, ABTS, FRAP,
PHEN), antibacterial properties (E. coli, Pseudomonas, Staphylococcus), and
anti-inflammatory effects. The results recorded were highly satisfactory. The
second phase was dedicated to preparing the cream with different active
substance concentrations (2%, 5%, 10%), evaluating its pH, viscosity, stability,
organoleptic characteristics, and conducting in vivo tests. The formulation results
are very encouraging and promising.
