Extraction des huiles essentielles et des extraits de deux plantes médicinales (Eucalyptus globulus et Origanum Vulgare) en vue d’une formulation d’un vicks dermique anti-inflammatoire

Abstract

The aim of this work is to formulate a Vicks ointment based on the essential oils of two medicinal plants: eucalyptus globulus and origanum vulgare, which can be extracted by different conventional or innovative methods. Our goal is to obtain an organic essential oil; therefore, we have been interested in extraction by hydrodistillation of the Clevenger type, which is commonly used in pharmacology. The second formulation of this product is based on the use of plant extracts obtained by the maceration technique applied to the same plants. Before that, the effectiveness of these different essential oils and extracts will be evaluated by carrying out physicochemical analyses and examining their antioxidant, anti-inflammatory, antibacterial and antifungal properties, as well as by carrying out toxicity assessments on mealworms. Vicks ointment is mainly used for its therapeutic effects in reducing nasal congestion and coughs. For this, a thorough examination of its physicochemical characteristics, such as pH, viscosity and stability, is essential, as well as a comparison with a reference Vicks product.